研究業績

2015年

原著論文

• "Role of elevated serum uric acid levels at the onset of overt nephropathy in the risk for renal function decline in patients with type 2 diabetes"
  K. Tanaka, S. Hara, M. Hattori, K. Sakai, Y. Onishi, Y. Yoshida, S. Kawazu and A. Kushiyama
  J Diabetes Investig 6, 1, 98-104 (2015).

  • URL
  • DOI: 10.1111/jdi.12243

  25621139
• "DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-kappaB activation"
  T. Shinjo, Y. Nakatsu, M. Iwashita, T. Sano, H. Sakoda, H. Ishihara, A. Kushiyama, M. Fujishiro, T. Fukushima, Y. Tsuchiya, H. Kamata, F. Nishimura and T. Asano
  Am J Physiol Endocrinol Metab 309, 3, E214-23 (2015).

  • URL
  • DOI: 10.1152/ajpendo.00553.2014

  26015438
• "Protection from diet-induced obesity and insulin resistance in mice lacking CCL19-CCR7 signaling"
  T. Sano, M. Iwashita, S. Nagayasu, A. Yamashita, T. Shinjo, A. Hashikata, T. Asano, A. Kushiyama, N. Ishimaru, Y. Takahama and F. Nishimura
  Obesity (Silver Spring) 23, 7, 1460-71 (2015).

  • URL
  • DOI: 10.1002/oby.21127

  26097021
• "Mosapride citrate improves nonalcoholic steatohepatitis with increased fecal lactic acid bacteria and plasma glucagon-like peptide-1 level in a rodent model"
  H. Okubo, Y. Nakatsu, H. Sakoda, A. Kushiyama, M. Fujishiro, T. Fukushima, Y. Matsunaga, H. Ohno, M. Yoneda, H. Kamata, T. Shinjo, M. Iwashita, F. Nishimura and T. Asano
  Am J Physiol Gastrointest Liver Physiol 308, 2, G151-8 (2015).

  • URL
  • DOI: 10.1152/ajpgi.00198.2014

  25428903
• "The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model"
  Y. Nakatsu, Y. Seno, A. Kushiyama, H. Sakoda, M. Fujishiro, A. Katasako, K. Mori, Y. Matsunaga, T. Fukushima, R. Kanaoka, T. Yamamotoya, H. Kamata and T. Asano
  Am J Physiol Gastrointest Liver Physiol 309, 1, G42-51 (2015).

  • URL
  • DOI: 10.1152/ajpgi.00443.2014

  25999428
• "Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the gamma subunit"
  Y. Nakatsu, M. Iwashita, H. Sakoda, H. Ono, K. Nagata, Y. Matsunaga, T. Fukushima, M. Fujishiro, A. Kushiyama, H. Kamata, S. Takahashi, H. Katagiri, H. Honda, H. Kiyonari, T. Uchida and T. Asano
  J Biol Chem 290, 40, 24255-66 (2015).

  • URL
  • DOI: 10.1074/jbc.M115.658559

  26276391
• "High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice"
  T. Shinjo, Y. Nakatsu, M. Iwashita, T. Sano, H. Sakoda, H. Ishihara, A. Kushiyama, M. Fujishiro, F. Nishimura and T. Asano
  Diabetol Metab Syndr 7, 50 (2015).

  • URL
  • DOI: 10.1186/s13098-015-0047-y

  26097511
• "Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus"
  S. Qiang, Y. Nakatsu, Y. Seno, M. Fujishiro, H. Sakoda, A. Kushiyama, K. Mori, Y. Matsunaga, T. Yamamotoya, H. Kamata and T. Asano
  Diabetol Metab Syndr 7, 104 (2015).

  • URL
  • DOI: 10.1186/s13098-015-0102-8

  26594248
• "LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis"
  Y. Matsunaga, Y. Nakatsu, T. Fukushima, H. Okubo, M. Iwashita, H. Sakoda, M. Fujishiro, T. Yamamotoya, A. Kushiyama, S. Takahashi, Y. Tsuchiya, H. Kamata, F. Tokunaga, K. Iwai and T. Asano
  Mediators Inflamm 2015, 125380 (2015).

  • URL
  • DOI: 10.1155/2015/125380

  26170532
• "Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines"
  R. Kanaoka, A. Kushiyama, Y. Seno, Y. Nakatsu, Y. Matsunaga, T. Fukushima, Y. Tsuchiya, H. Sakoda, M. Fujishiro, T. Yamamotoya, H. Kamata, A. Matsubara and T. Asano
  PLoS One 10, 6, e0127467 (2015).

  • URL
  • DOI: 10.1371/journal.pone.0127467

  26039047